Warnings and Precautions

ChiroRab

Tell your doctor or nurse before you or your child receives ChiroRab for post-exposure prophylaxis if you/your child:

Have/has a severe allergy to egg or egg products. ChiroRab contains residues of chicken proteins left over from the manufacturing process.
Have/has a severe allergy to the antibiotics neomycin, chlortetracycline, or amphotericin B. These antibiotics may be present in tiny amounts in the vaccine.
Have/has a severe allergy to polygeline.

Fainting can occur following or even before any needle injection. Tell the doctor or nurse if you fainted due to a previous injection.

Cases of infrequent but severe conditions affecting the nervous system have been reported following the receipt of ChiroRab® vaccine. Anti-inflammatory medicines (steroids), often used to treat these conditions, may interfere with the vaccine’s effectiveness (see below, other drugs and ChiroRab®). Your doctor or nurse will decide how to proceed in this circumstance.

As with all vaccines, ChiroRab may not fully protect all vaccinated people. The vaccine should not be given into the buttocks, under the skin, or into a blood vessel.

Other Medicines and ChiroRab

Inform your doctor about your medication history and plans to take new medicines, if any. Unless your doctor tells you otherwise, you/your child should continue to take all prescribed medication as usual.

If you or your child already has a poor immune system or is already taking medicines that reduce the body’s immunity to infections, ChiroRab can still be given, but you/your child may not be as well protected as other people. In this case, your/your child’s doctor may decide to carry out blood tests after the vaccine administration, to check if the body has produced enough antibodies to the virus. If necessary, you/your child will be given extra vaccine doses.

ChiroRab can be given at the same time as other inactivated vaccines. Each type of vaccine has a different injection site.

You/Your child may also need to be given an injection of antibodies against rabies (called “rabies immunoglobulin”) if you or your child has not been fully vaccinated against rabies and you or your child has likely been infected with the virus. If so, the rabies immunoglobulin injection (given only once and usually with the first dose) and the vaccine will be given in different parts of the body.

Before any possible contact with the Virus

If you/your child has never had any rabies vaccine before:

You need to have three doses in the first instance. The first dose is given at the first visit, the second dose is given seven days later, and the third dose is 21 or 28 days after the first dose.
If you are an adult between 18 and 65 years of age needing rapid protection, ChiroRab can also be given in three doses over seven days. The first dose is given at the first visit, the second dose is given three days later, and the third dose is given four days after the second dose.
If you/your child miss an appointment for an injection, you should arrange to have it as soon as possible after the due date.

The need for boosters depends on the risk of contact with the rabies virus. Your doctor will consult the official rabies vaccination recommendations and tell you when a booster is needed.

If you are someone who is always at a high risk of infection, your doctor may also ask you to have regular blood tests to measure the amount of antibody against rabies in your blood so that boosters can be given as soon as needed. Experience shows that booster doses are generally required every 2-5 years.

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ChiroRab